4 ACO DMT FOR SALE
Buy 4 ACO DMT Online, 4-AcO-DMT (or psilacetin) is a semi-synthetic tryptamine closely related to the “magic mushroom” molecules psilocin and psilocybin. Like psilocybin, it appears to be metabolized by the body into psilocin.. Buy 4-AcO-DMT for sale
While there are studies done on the use of serotonin 5-HT2A agonists in treating substance/drug use disorders, the neurological basis of these effects have yet to be elucidated. There is an interesting study done on the effects of 4-Aco-DMT on drug-dependent rats and mice, published in the European Journal of Neuroscience (EJN). Buy 4-AcO-DMT for sale
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Chronic use of drugs of abuse produce changes and cellular adaptations in neurons located in the VTA (Ventral Tegmental Area) of the brain, which is part of the dopamine mediated reward pathway. These adaptations are mediated by BDNF (brain-derived neurotrophic factor) and are associated with the aversive withdrawal motivation that leads to a drug-dependent state. There is growing evidence that suggests that 5-HT2A receptor signaling can regulate the expression of BDNF in the brain. Both 5-HT and TrkB singaling are involved in modulating long term neuronal survival and plasticity but it is still unknown if these effects occur via a direct 5HT2A/TrkB interaction or downstream interactions between 5HT2A signalling/BDNF signalling.
In a study done with 4-Aco-DMT, it was observed that a single administration to the VTA of rats and mice blocks the aversive conditioned response to drug withdrawal as well as the mechanism that switches the drug-naive state to a drug-dependent system.
These studies indicated that 5-HT2A agonists can be used as therapeutic agents to reverse drug dependency and inhibit the aversive withdrawal response.
Our batch of 4-AcO-DMT has been used in scientific research as a standard for purity analysis, and has been confirmed as near 100% purity in a published paper from the University of Massachusetts: https://psychedelicreview.com/the-crystal-structure-of-4-aco-dmt-fumarate/ Buy 4-AcO-DMT for sale
4-AcO DMT Dosage
It is usually sold as a fumarate salt (4-AcO-DMT fumarate) containing on average 1 mg pure 4-AcO-DMT for every 1.24 mg of the powder. Or if it’s a hydrochloride salt, it will contain on average 1 mg pure for every 1.15 mg of the powder. In practice the difference may be negligible, but it’s worth knowing.
- Oral dosage (approximate) (according to Erowid)
- Threshold of effect: 5-10 mg
- Low: 10-20 mg
- Common: 20-30 mg
- Strong: 30-50 + mg
Effects of 4-AcO DMT and how long DMT lasts in the body
Surprisingly the effects of the molecule are close to those felt with magic mushrooms like those of the psilocybe genus. It is very representative of this adage. The overall duration of the trip is about 3 to 6 hours, depending on the dose and the person.
Desired effects of 4-AcO DMT
- Physical and intellectual stimulation
- Feeling of euphoria
- Increased sociability
- Want to express yourself and go to others
- Feeling of well-being
- Exacerbation of the senses
- Unbridled libido
Risk of consuming 4-AcO DMT
The relative toxicity of 4-AcO-DMT and more specifically neurologically is a fortiori low, as is the psilocine: almost no neurotoxicity. But these are only exageration and the reality is that no serious scientific study has been conducted on the subject.
Notably, physical risks including vomiting, loss of consciousness, and seizures, but these are fairly uncommon. As far as we know, nobody has died from taking it nor is it likely to be physically dangerous for most people.
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As with any psychedelic, it should probably be avoided by pregnant or breastfeeding women or anyone prone to seizures. Basically heart problems, blood pressure problems, or mental health issues like severe anxiety. If only to err on the side of caution given the lack of clinical research.
- Puffs of anxiety
- Psychosis crisis
- Tachycardia and hypertension
- Abundant perspiration and hyperthermia
- Tight jaws
- Loss of appetite
- Want to resume / Craving
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